The days are getting closer and closer and we’re one more day away from the NFL getting kicked off on Thursday that will be followed up with a full slate of games this Sunday. A great NFC West rivalry matchup is on the table between the San Francisco 49ers and the Arizona Cardinals.

Both the 49ers and Cardinals had pretty even matchups last season, but San Francisco ended up coming out on top in both games.

It’s the first time we will get a look at DeAndre Hopkins in Cardinal red and Trent Williams in scarlet and gold. The 49ers are primed to repeat last seaons’s success, while the Cardinals are on the come-up with a taltned young QB in Kyler Murray.

It’s going to be a fun game to watch and even though it’s only Week 1, it’s a divisional matchup that is going to be key down the road.

With that being said, let’s take a look at four major X-Factors to watch in the Arizona Cardinals vs. San Francisco 49ers matchup in Week 1 of the 2020 NFL season.