Fantasy Football: 5 must-play rookies in Week 4 NFL action

Brandon Aiyuk, 49ers
Robert Deutsch-USA TODAY Sports

4. Brandon Aiyuk, San Francisco 49ers

Aiyuk was kept out of the season-opener due to an injury but he is back on the field and playing well. In Week 4, the 49ers have a favorable matchup against the Philadelphia Eagles.

Last week against the New York Giants, Aiyuk finished with five catches for 70 yards. The 49ers have been searching for wide receivers for quite some time and they are hoping Aiyuk is the next big thing. He seemed to fit well in the offense and that is why he is start-worthy this week.

There are problems in Philadelphia on both sides of the ball. The secondary was supposed to be improved but that has not been the case.

No matter what quarterback plays for San Francisco, Aiyuk will be one of the most targeted players within the offense. He is a flex player in Week 4 because of the matchup.

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