The Indianapolis Colts picked up a huge victory in Week 3 when they defeated the Kansas City Chiefs for their first victory of the season. They were looking to ride that momentum in their Week 4 matchup with the Tennessee Titans and get things going. Disappointingly for them, it was another flat performance.

The Colts lost 24-17, as they dug themselves an early hole that they were unable to climb out of. Tennessee led by as many as 21 points in the game as the Colts’ defense struggled to mount any resistance early in the game.

A big reason for their struggles on that side of the ball thus far this season has been the absence of star linebacker, Shaquille Leonard. Leonard missed the first three games of the season as he was recovering from off-season surgery on his back. The All-Pro was able to make his season debut against the Titans, but it was a short-lived one.

He played for only 16 snaps before suffering a concussion. That is a huge blow for the Colts, as they have a quick turnaround playing on Thursday Night Football against the Denver Broncos. Unfortunately for them, they will be without Leonard for that game.

He was ruled out on Monday, meaning the Colts will be without one of their best players for the fourth time in five games. It could not have come at a worse time as Thursday night games are tough enough to win while at full strength. Having to travel on a short week and being short-handed will make it that much tougher.

Leonard isn’t the only player that the Colts are going to be without this week. Defensive lineman Tyquan Lewis is also in concussion protocol and will miss this week’s game against the Broncos.

Star running back Jonathan Taylor is also ailing. He injured his ankle against the Titans and the team is going to take their time evaluating him. Taylor has yet to be ruled out but his availability is certainly up in the air.