The Los Angeles Rams’ defense of their Super Bowl victory has been tough sledding thus far. They are 2-2 heading into Week 5 as they have struggled to find consistency and put together a complete performance in every facet of the game.

One week the offense looks good but the defense sputters a little bit. Another is the opposite, but then the special teams have a breakdown as well. There is a lot for head coach Sean McVay to still iron out, but he has shown that he is more than capable of handling it. Alas, that job will get tougher without the services of multiple starters.

An offensive line that has already struggled mightily will be without starting center Shelton Coleman for at least 4-6 weeks after suffering a high ankle sprain. Coleman had won the competition for the starting right guard spot in training camp but was moved over to center when Brian Allen suffered an injury of his in Week 1.

The Rams have dipped deep into their offensive line depth as they are using third-stringers at a few spots. With Coleman now sidelined, that means the entire starting interior of the offensive line is all out. That spells trouble for a Rams offensive line that has already been struggling opening up holes in the running game and protecting Matthew Stafford.

In addition to Coleman, the team also lost safety Jordan Fuller. The third-year man out of Ohio State has struggled to stay on the field this season, as he also missed the team’s Week 3 matchup with the Arizona Cardinals.

Fuller suffered a hamstring injury against the 49ers on Monday Night Football that will keep him sidelined for 2-4 weeks. It is a sizable blow as Fuller played 74 percent of the snaps in Week 5, his highest percentage of the season.

Without Fuller in the lineup, Taylor Rapp will likely be asked to play a larger role on the defense. While listed as the starter, Rapp played only 50 percent of the snaps against the 49ers.